"Sergio Aguero will be assessed by club doctors today after being involved in a road accident on Thursday. The City forward was in Holland on his day off and has sustained injuries," said the statement.
Argentine newspaper Diário Olé said Aguero, who was in the Netherlands to attend a concert, was riding in a taxi when the vehicle crashed into a pole.
His former club in Argentina, Independiente, said on Twitter: "Strength and fast recovery. All Independiente is with you at this difficult time."
Premier League leaders City face Chelsea at Stamford Bridge on Saturday.